NAD+
6 indexed publications · 4 human studies · research from 2003 to 2026
A cellular coenzyme, not a peptide. Selected studies examine infusion metabolism, tolerability, cardiac outcomes, and experimental renal physiology.
Research goals studied
- Bone, muscle & performance
- Cardiovascular
- Gene & DNA regulation
- Gut & digestion
- Immune function
- Kidney, liver & organ
- Longevity & aging
- Metabolic & glucose
- Mood, stress & sleep
- Neuro & cognition
Studies referencing NAD+
Metabolism of Nicotinamide Adenine Dinucleotide+ in Atherosclerosis: Mechanisms and Nutritional Modulation.
2026 · Preclinical
View source (PMID: 42776599)Intravenous infusion of nicotinamide adenine dinucleotide (NAD + ) versus nicotinamide riboside (NR): a retrospective tolerability pilot study in a real-world setting.
2026 · Frontiers in aging · Human evidence
Direct NAD intervention; not evidence for NR/NMN precursor supplementation or general anti-aging benefit.
View source (PMID 41704678 ; DOI 10.3389/fragi.2026.1652582)Effect of Nicotinamide Adenine Dinucleotide on Heart Failure Caused by Ischemic Cardiomyopathy: A Randomized, Placebo-Controlled Trial.
2026 · American journal of cardiovascular drugs : drugs, devices, and other interventions · Human evidence
Direct NAD intervention; not evidence for NR/NMN precursor supplementation or general anti-aging benefit.
View source (PMID 40954388 ; DOI 10.1007/s40256-025-00764-7)Effect of Intravenous Nicotinamide Adenine Dinucleotide on Left Ventricular Function After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction: A Randomized Controlled Trial.
2026 · American journal of cardiovascular drugs : drugs, devices, and other interventions · Human evidence
Direct NAD intervention; not evidence for NR/NMN precursor supplementation or general anti-aging benefit.
View source (PMID 42961639 ; DOI 10.1007/s40256-026-00826-4)A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD.
2019 · Frontiers in aging neuroscience · Human evidence
Direct NAD intervention; not evidence for NR/NMN precursor supplementation or general anti-aging benefit.
View source (PMID 31572171 ; DOI 10.3389/fnagi.2019.00257)Renal haemodynamics and natriuretic responses to intravenous administration of diadenosine tetraphosphate (Ap4A) and nicotinamide adenine dinucleotide (NAD) in rat.
2003 · Journal of physiology and pharmacology : an official journal of the Polish Physiological Society · Preclinical
Direct NAD intervention; not evidence for NR/NMN precursor supplementation or general anti-aging benefit.
View source (PMID 12832719)
Working with NAD+?
Convert a vial to draw volume on the peptide calculator, or track protocols and vials in the free app.
Start tracking free